April 17, 1968 at Tiger Stadium
Tigers 4, Indians 3 (5-1)
The Tigers picked up their fifth straight win and their second extra inning win in three games in their opener against the Indians. Willie Horton provided the heroics with a two run, walk off homer in the bottom of the tenth inning to win it for Detroit. Mickey Stanley had a nice game as well at the plate and he went two for five with an RBI.
Denny McLain got his second no decision of the season with seven solid frames. He gave up two runs on six hits and two walks with nine strikeouts. Jon Warden picked up his second win of the season as he got the final two batters out in the tenth inning.